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Mortality and Risk Factors in Psychiatric Inpatient with Dementia: A 13-year Long-Term Data Analysis

Author(s): Ruey Chen, Wu-Chien Chien, Hsin Chu, Huei-Ling Chiu, Chi-Hsiang Chung, Chyn-Yng Yang, Nae-Fang Miao, Kuei-Ru Chou, RN



The study aimed at identifying mortality and risk factors of psychiatric inpatients with dementia, a 13-year long-term data analysis.


This study adopted retrospective cohort design. The original claims data of 1 million randomly sampled beneficiaries between 1997 and 2010 from Taiwan’s National Health Insurance Research Database were analyzed. Mortality risk and risk factors were assessed using Cox regression analysis.


Among 320 dementia patients, a total of 83.4% had Alzheimer disease and 16.6% had vascular dementia. The mortality rates within 1 year after admission were reported for patients with vascular dementia (41.7%) and patients with Alzheimer disease (19.1%). A 1-year increase in age was associated with 3% increase in the risk of hospitalization mortality. Mortality risk among male inpatients was 2.9 times higher than that of female inpatients (P<0.001). The mortality risks among delirium inpatients, those with delusional symptoms, and those with depression had hazard ratios of 2.84 (P=0.004), 2.17 (P=0.008), and 1.82 (P=0.075) respectively, relative to inpatients with uncomplicated symptoms.


The factors that influenced the mortality of dementia patients admitted to the psychiatric department were male sex, old age, delirium symptoms, and delusional symptoms.

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