Impact of Transcranial Direct Current Stimulation on Patients with Parkinsons disease: A report of 2 cases

ABSTRACT Introduction: The motor function is associated with the activity of both the motor and prefrontal cortices. The efficacy of tDCS over specific brain cortices has been examined in many psychiatric and neurologic disorders. The aim of this study is report of the tDCS effects on two female of advanced age, with idiopathic PD Methods: We considered 50-minute sessions of bi-lateral primary motor cortices as well as left DLPFC anodal stimulation using tDCS with passive stretching exercises simultaneously for a total of 20 sessions in 7 weeks. Clinical signs and EEG waveform were assessed at distinct times. Results: Both of the two patients showed improvement in motor function for a short time. EEG changes to some extent were in relation to clinical states. Conclusions: It seems that tDCS can be an auxiliary treatment for motor dysfunction in Parkinson’s disease, however, further studies must be carried out in order to prove the claim. Keywords Parkinson’s disease; Transcranial direct current stimulation

Abstract

Introduction: The motor function is associated with the activity of both the motor and prefrontal cortices. The efficacy of tDCS over specific brain cortices has been examined in many psychiatric and neurologic disorders. The aim of this study is report of the tDCS effects on two female of advanced age, with idiopathic PD Methods: We considered 50-minute sessions of bi-lateral primary motor cortices as well as left DLPFC anodal stimulation using tDCS with passive stretching exercises simultaneously for a total of 20 sessions in 7 weeks. Clinical signs and EEG waveform were assessed at distinct times. Results: Both of the two patients showed improvement in motor function for a short time. EEG changes to some extent were in relation to clinical states. Conclusions: It seems that tDCS can be an auxiliary treatment for motor dysfunction in Parkinsonâ??s disease, however, further studies must be carried out in order to prove the claim.