All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.


The Polymorphisms of DRD2 141-C Ins/Del Receptor Influenced the Treatment Responses of Schizophrenia Patients

Author(s): Saidah Syamsuddin, Irawan Yusuf , Jayalangkara Tanra, Irfan Idris

Polymorphisms of DRD2 receptors lead to vary in the treatment responses of schizophrenia patients.
Objectives: This study carried out to know the association of polymorphisms of DRD2 141-C Del/Ins receptors to the doses needed of antipsychotic drug, length of hospital stay, and improvement of symptoms of schizophrenia patients.

Methods: The 208 of schizophrenia patients recruited in this study, was hospitalized and have given haloperidol (first generation of antipsychotic drug) then the treatment responses were evaluated by CGI score. The genotyping of the blood performed for DRD2 receptors polymorphisms.

Results: This study showed that DD genotype needed higher doses of antipsychotic drugs (p<0,05), have longer hospital stay (p<0,05), and have a minimum improvement of symptoms (p<0,05).

Conclusion: It was concluded that polymorphisms of DRD2 141-C Del/Ins receptors influenced the treatment responses and should be considered when treating schizophrenia patients with haloperidol.


Full-Text | PDF

Share this       

antalya escort

izmir rus escort

bursa escort bayan

antalya escort bayanlar

izmir escort

porno indir

porno izle

mobil porno

eskişehir escort

burdur escort

bartın escort


türk takipçi satın al

izmir escort

bursa escort

türk porno

escort bayan

yabanci porno

takipçi satın al

takipçi satın al

instagram takipçi satın al

instagram beğeni satın al

adana escort

takipçi satın alma

izmir escort

konya escort

instagram takipçi satın al


instagram takipçi satın al

takipçi satın al

spotify takipçi

tiktok takipçi satın al

instagram keşfet satın al

escort feke

takipçi satın al instagram

takipçi instagram satın al

eskişehir bayan escort

bursa escort bayan

smm gerçek panel

etiler escort

soğanlı escort

erenköy escort

maslak escort

küçükyalı escort

ortaköy escort

bostancı escort

taksim escort

çağlayan escort

eyüpsultan escort

kozyatağı escort

nişantaşı escort

anadolu yakası escort

avrupa yakası escort

bahçelievler escort

silivri escort

kadıköy escort

beylikdüzü escort

şile escort

esenler escort

paper io



Elektronik Sigara