Abstract

Neurobiology of depression: findings, controversies and perspectives

Author(s): Juliane Minkwitz,Hubertus Himmerich

Despite profound scientific efforts, the neurobiology of depression is poorly understood and the literature reveals many inconsistencies. Nevertheless, we would like to highlight the most impressive findings regarding genetics, gene expression, epigenetics, neuroanatomy, neurochemistry, neuroendocrinology and the neuroimmunology of depression, possibly directing psychiatric research towards novel antidepressant drug targets.