All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.


Disrupted Resting-State Brain Functional Architecture in Amphetamine-Type Stimulant Abusers

Author(s): Qun Chen, Dang Zheng, Shaojuan Cui, Kai-Juan Yan,Chen-xiao Fan, Guo-fu Zhang, Le Xiao, Yan Li, Xiao-fei Yuan, Kankan Xie, Yaqiong Li, Xiao-nian Luo, Yuan Zhou, Zhan-Jiang Li


Background: The abuse of amphetamine-type stimulants has continued to increase, leading to new challenges to human health. However, the effects of the abuse of amphetamine-type stimulants on brain functional networks are unclear. The aim of the current study was to use resting-state functional magnetic resonance imaging (rs-fMRI), a technique that is used to study the brain’s intrinsic functional organization, to characterize the brain functional
architecture influenced by amphetamine-type stimulant abuse.

Methods: The present study recruited seventeen male amphetamine-type stimulant abusers (ATSAs) and twenty-two healthy male controls. We used degree centrality (DC) and seed-based resting-state functional connectivity (RSFC) analyses to identify brain functional architecture differences between ATSAs and healthy controls (HCs).

Results: The ATSA group showed a decreased DC, especially in a large cluster including the right anterior, middle, and posterior insula. Furthermore, seed-based RSFC analyses revealed decreased functional connectivity in a network composed of the right posterior insula, medial prefrontal cortex, visual and sensorimotor cortices as well as in a network composed of the right middle insula and visual cortices in the ATSA group.

Conclusion: These results provide evidence that the resting-state brain functional architecture is disrupted in amphetamine-type stimulant abusers from a network perspective.

Full-Text | PDF

Share this       

antalya escort

izmir rus escort

bursa escort bayan

antalya escort bayanlar

izmir escort

porno indir

porno izle

beşiktaş escort

eskişehir escort

burdur escort

bartın escort


türk takipçi satın al

izmir escort

bursa escort

türk porno

escort bayan

yabanci porno

takipçi satın al

takipçi satın al

instagram takipçi satın al

instagram beğeni satın al

instagram takipçi satın al

takipçi satın alma


panel smm

takipçi satın al instagram

smm panel

ataköy escort

izmit escort