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Brain imaging correlates of emerging psychiatry

Author(s): Stahl SM

The early detection of the schizophrenia prodrome in young people considered ‘at-risk‘ of developing this severe mental illness has entered mainstream clinical practice despite the limitations in the predictive specificity of the clinical criteria that define the At-Risk Mental State syndrome. These limitations are increasingly addressed by brain imaging research, which has added substantial evidence to the notion of emerging and progressive gray and white matter abnormalities in the early phase of illness. The association of the apparent neuropathology with the clinical signs and symptoms of the disorder – along with cognitive impairment and the underlying pathophysiology – will be reviewed.

Borderline personality disorder is a mental health condition that affects how you think and feel about yourself and others, leading to difficulties in daily living. It includes challenges with self-esteem, trouble controlling emotions and conduct, and a history of shaky relationships. BPD is a significant mental illness marked by extreme mood swings and relationship difficulties. BPD patients experience intense emotions, and bouts of rage, anxiety, or melancholy might last for days.

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