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Between Autistic Spectrum Disorder (ASD) and Childhood Onset Schizophrenia (COS): A Case Report

Author(s): Galli Carminati G, Cecile Crettol, Federico Carminati


Even if childhood-onset of schizophrenia is described in the literature, and there are several case reports of concomitant autism spectrum disorders (ASD) and childhood-onset schizophrenia (COS), early diagnosis remains less the rule than the exception.


We report the detailed clinical history of a young woman with ASD and childhood onset schizophrenia from birth to the age of 26. The evolution of the state of the patient is reported together with the diagnosis provided by the caregivers and the pharmacological and psychological treatment.


The delay in formulating a diagnosis of concomitant ASD and COS as well as the pressure on academic achievement have contributed to the patient’s sequel of crisis and relapses. The clinical status of the patient has presented a marked improvement when the comorbidity has been acknowledged and properly treated, both pharmacologically and via an appropriate reduction of the stressful proficiency requirements.


Early diagnosis of psychiatric comorbidities in ASD allows a more effective therapeutic strategy and the adoption of a psychopedagogical approach adapted to the vulnerability of these patients with respect to stress.

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