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Adherence to antidepressants: A review of the literature

Author(s): Dra. Maria-Jose Martin-Vazquez

We have revised literature related to antidepressant adherence published in the last 15 years in Spanish and English. Adherence of antidepressants is a major problem all over the world, which affect response, cost of the illness and risk of relapse. Persistence in the treatment is important to avoid relapses and to ensure remission, but in many cases the lack of accurate information causes an early interruption of treatment. Some other sociodemographic factors seem to be common to bad adherence, as low income, low socioeducational status, severity of depression, difficult access to physicians or to the medication.

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