Development of colostrum MAF and its clinical applicationAuthor(s): Haruka Amitani, Robert A Sloan, Nanami Sameshima, Koichi Yoneda, Marie Amitani, Akinori Morinaga, Yoshihiro Uto, Toshio Inui, Akio Inui, Akihiro Asakawa
Recently, immunotherapy has emerged as a new and appealing strategy for cancer treatment and various other acute and chronic diseases. Essential components of the natural immune system-phagocytic cells called macrophages-multiply in response to an infection in the body. The use of a macrophage activating therapy, such as macrophage activating factor (MAF), has extensive applications for treating numerous diseases by activating the natural macrophages of the body to stimulate the immune system. The aim of this review is to provide insight into the features and clinical efficacy of a new type of macrophage-activating factor derived from colostrum, called colostrum MAF.